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What are the prodromal symptoms of a tyramine-induced hypertensive crisis?

Headache, stiff neck, nausea, vomiting, and sweating

The prodromal symptoms of a tyramine-induced hypertensive crisis typically include headache, stiff neck, nausea, vomiting, and sweating. This condition occurs when individuals taking monoamine oxidase inhibitors (MAOIs) ingest tyramine-rich foods, leading to a sudden increase in blood pressure. The headache is often severe and is one of the hallmark symptoms signaling an impending hypertensive episode. Additionally, a stiff neck can occur as a result of elevated blood pressure or tension. Nausea, vomiting, and sweating can also manifest due to vasoconstriction and the body's response to the increased blood pressure and accompanying stress.

While the other options present symptoms that could relate to various medical conditions or side effects, they do not specifically align with the classic presentation of a tyramine-induced hypertensive crisis. Recognizing these particular symptoms is crucial for healthcare professionals to identify and address the situation promptly to prevent severe complications.

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Orthostatic hypotension, insomnia, and edema

Paresthesias, myoclonus, and muscle pain

Irritability, confusion, dizziness, and cardiac arrhythmia

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